ALBUMIN DEFICIENCY

What is Albumin?

Albumin is the most abundant blood plasma protein that is synthesized in the liver. It plays an important role in hemodynamics by providing oncotic pressure inside plasma.

A person may have hypoalbuminemia (or low albumin levels) for many reasons. Dietitians use the serum albumin level as an indicator of protein malnutrition, though other situations may cause a low albumin level (stress, surgery, impaired liver function or overhydration of body tissues).

How Albumin Deficiency can occur in body?

  • Malnutrition
  • Lack of adsorption
  • The conditions increased need in the body conditions (pregnancy, hyperthyroidism etc)
  • Lack of synthesis of Albumin
    • Liver diseases ( acute or chronic)
    • Chronic infection
    • Congenital Albumin Deficiency,
    • Congestive Heart failure
  • İncrease in the destruction of Albumin;
    • Trauma
    • Infection
    • Cancer
    • Fever
    • Antimetabolites
    • Some of the hypermetabolic diseases (Cushing syndrome, preeclampsia,thyrotoxicosis etc)
  • İncrease in loss of Albumin;
    • Burns,
    • Edema,
    • Acid,
    • Bleeding,
    • Nephrotic Syndrome
    • Enteropathy
    • Trauma
  • Lack of Dilutional (Giving intravenous fluids, water poisoning, psychogenic diabetes)
 

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