What is Albumin?

Albumin is the most abundant blood plasma protein that is synthesized in the liver. It plays an important role in hemodynamics by providing oncotic pressure inside plasma.

A person may have hypoalbuminemia (or low albumin levels) for many reasons. Dietitians use the serum albumin level as an indicator of protein malnutrition, though other situations may cause a low albumin level (stress, surgery, impaired liver function or overhydration of body tissues).

How Albumin Deficiency can occur in body?

  • Malnutrition
  • Lack of adsorption
  • The conditions increased need in the body conditions (pregnancy, hyperthyroidism etc)
  • Lack of synthesis of Albumin
    • Liver diseases ( acute or chronic)
    • Chronic infection
    • Congenital Albumin Deficiency,
    • Congestive Heart failure
  • İncrease in the destruction of Albumin;
    • Trauma
    • Infection
    • Cancer
    • Fever
    • Antimetabolites
    • Some of the hypermetabolic diseases (Cushing syndrome, preeclampsia,thyrotoxicosis etc)
  • İncrease in loss of Albumin;
    • Burns,
    • Edema,
    • Acid,
    • Bleeding,
    • Nephrotic Syndrome
    • Enteropathy
    • Trauma
  • Lack of Dilutional (Giving intravenous fluids, water poisoning, psychogenic diabetes)

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