IMMUNO DEFICIENCY

What is Immune Deficiency?

Depending on the inherited genetic defects , primary immune deficiences are diseases that are characterized by functioning disorders of the immune system.

In Primary B-cell immune failures syptoms occur after 6 months of born due to protection of maternal antibodies.

Early diagnosis and genetic counseling are important for right treatment.

Every step that impacts the emergence of an immune response create a potential for primary immune deficiency.

Secondary immune deficiency may occur due to cancers (especially leukemia and lymphoma)or while treatment of cancers with immunosuppressive or cytotoxic (immunosuppressive) drugs or radiotherapy, or both used ,also bone marrow and other transplant recipients (transplant) regimes, splenectomy (spleen retrieval operation) or some infections (eg, human immunodeficiency virus infection / acquired immunodeficiency syndrome)

Auto Immune Diseases

Autoimmune diseases occcur when immune system doesn't identify and start to fight own body tissues. The reason of diease is unclear but in some cases it is tested that it occurs more frequently in people with genetic predisposition and some microorganisms and medicines trigger autoimmune disease. A single organ or a few organs and tissues may be affected by this disease.

Examples of Autoimmune Diseases: Rheumatoid Arthritis, Systemic Lupus Erythematosus (SLE), Dermatomyositis and severe muscle wasting diseases (Guillain-Barre, Myasthenia gravis). 

 

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